Chemosensory Functions for Pulmonary Neuroendocrine Cells

Chemosensory functions for pulmonary neuroendocrine cells.

The mammalian airways are sensitive to inhaled stimuli, and airway diseases are characterized by hypersensitivity to volatile stimuli, such as perfumes, industrial solvents, and others. However, the identity and function of the cells in the airway that can sense volatile chemicals remain uncertain, particularly in humans. Here, we show that solitary pulmonary neuroendocrine cells (PNECs), which...

Pulmonary neuroendocrine cells in chronic renal failure.

In patients with chronic renal failure, mechanical and haemodynamic changes could occur in the lungs without obvious pulmonary symptoms and findings, and their effects could pave the way to pulmonary functional disorders. Numerous studies have demonstrated that the respiratory system is a site of synthesis of many compounds, which play biological roles ascribed to hormones. The present article ...

[APUD cells. The human pulmonary neuroendocrine system].

Pulmonary neuroendocrine cells and lung development: dim outlines emerge.

Pulmonary Large-Cell Neuroendocrine Carcinoma

Lung neuroendocrine tumors are a heterogeneous sub-type of pulmonary cancers representing approximately 20% of all lung cancers, including small-cell lung cancer (SCLC) and large-cell neuroendocrine carcinoma (LCNEC). The frequency appears to be approximately 3% for LCNEC. Diagnosis of LCNEC requires attention to neuroendocrine features by light microscopy and confirmation by immunohistochemica...